I didn’t want to write about protein powder or the health benefits of apples today but I did want to briefly touch on an issue that I have been passionately researching for over a year. A full lenght article would take days to write and hours to read so this is just an intro to the idea of pharmaceutical integrity and what that means for you, the consumer/patient.
Few people are unaware that pharmaceutical industries lobby Doctors. We have all seen the shelves of samples and the posters and the calendars and the mugs and notepads in our Doctor’s offices. I have also worked closely to the legislative side of the health industry in Alberta and know that Big Pharma also puts on conferences and meetings to educate the Doctors on the newest developments, in particular, areas of medicine which they, no doubt, have the answer to in the form of a drug.
In fact, in some cases all of the information provided to Doctors and legislators regarding vaccines or other drugs comes directly from the pharmaceutical companies. And they do all of their own safety research and provide reports which, are not peer-evaluated by a third party group for accuracy, relevance and factuality. The information is also protected from being forcibly released to these peer groups in the interest of protecting the company’s profits. This is a very biased and very dangerous way of determining the safety and efficacy of a product. Not only that, but because of the profit reason, the FDA (I don’t know if Canada does this too) has been known to not report serious side effects of certain drugs.
Alive magazine has an article in their September 2006 issue called Bad Science, Could it be what ails you? that addresses the impact that funding can have on study outcomes or rather the interpretation of those outcomes. They are basing their article on a book written by a researcher (epidemiologist John Ioannidis) who stated that as much as more than half of research findings may be wrong.
The article makes such claims as “almost 16 percent of the scientists said they modified a study because of pressure from funders” and that ”in January 2006 CBC’s The National aired a three-part program exposing Dr. Chandra’s long-term pattern of scientific fraud and financial deception.” There are also references to studies that were said to lean to one conclusion but once peer reviewed were obviously leaning the other way. The article is available here: http://www.alive.com/4770a12a2.php
Big Pharma will spend billions of dollars making sure they inform you and your physician about their new products. It is a business. Adults see ads on TV, their Doctor’s offices and in magazines. They then think that they have adult ADD, or erectile dysfunction or IBS and ask their Doctors for a prescription. The Doctor obliges and starts a stream of unnecessary prescriptions. The worst part is that some of these diseases, like IBS, have actually been created by Big Pharma. Do you stay up at night thinking about work? Do you frequently go to the bathroom? You need drugs!
I had a Doctor prescribe me something for my asthma once. I don’t have asthma! I refused to take the drug until I had an asthma test confirming that I actually had asthma. The result of that test was, of course, negative. Did that deter my Doctor from attempting to give me drugs I didn’t need? NO! Or when I was pregnant I used to go in to my OB’s office and for every little complaint I had she had a prescription. I tore ALL of those up. I had a little bit of nausea for pete’s sake! Why was she prescribing me drugs for a bit of nausea?
In the movie Thank You For Smoking there is a line that the main character uses: “How would Big Tobacco benefit from the death of [cancer boy]? It’s in our best interest to keep him alive and smoking.”
It runs similarly for Big Pharma. It’s in their best interest to keep you sick (or thinking you are sick) for the rest of your life. Their business is selling drugs not enhancing health! That is why one in four visits to Canadian emergency rooms are attributed to side effects related to prescription drug use. One in four people in Canada that show up at the emergency room are being damaged by their “life-saving” drugs. 1.
Big Pharma is not an industry with much integrity. To emphasize that point there are a growing number of Doctors who are taking a “No Free-Lunch” pledge. This is a promise that they will not accept free-lunches or any other gifts from pharmaceutical industry representatives. They will instead base their prescription decisions on third party research and lower prices. When Doctors give you those free samples (which come directly from the companies) they are trying to get you to use the newest and most expensive drugs, instead of the similar, cheaper generic ones!
To show you the lack of integrity present in this industry I have combined a list of examples and their resources. Okay. I know most are from the National Post as I used to be a subscriber but it’s not like they aren’t reputable.
1. Medicine sending thousands to hospital 25% of admissions due to side effects. National Post Nov 1/06 -drug side effects in proper dosages and wrongfully administered drugs (drug names sound and are spelled similar etc.)
2. The politics of health “Profit Before People”-Jason Watkin (president of Biomedica Laboratories) -states that Big Pharma will rush products through safety trials to beat the competitor. They put profit above people’s safety.
3. National Post, Dec 12/07, page A12 has two good articles. ‘Unusual’ amount of allergic reactions to mumps shot put end to inoculations and Study links diabetes drugs to heart failure.
4. Cholesterol drugs don’t help ‘bulk’ of takers:study by Sharon Kirkey National Post (Don’t have the date on this one) -states that cholesterol lowering drugs don’t reduce the number of deaths in women and ONLY show an improvement in high risk men.
5.Class action to be launched over painkiller (oxycontin), National Post Sept 19/07
6. Vitamin C Overstatement – Student ‘blown away’ as science project results in fine for juice giantsNational Post A3, March 28/07 -this is related because GlaxoSmithKline (Big Pharma) was the manufacturer of this juice called Ribena in New Zealand which grossly overstated the Vitamin C content in the juice.
7. Another painkiller pulled off the shelves -Prexige National Post, Oct 5/07
8. Health Canada orders label change on Tamiflu to mention suicides National Post March 28/07 -gross side effects (psychosis)
9. The number behind the meds National Post, Oct 4/06 -How Big Pharm will manipulate data to make their products look favorable.
10. Pharmacy pamphlets omitting key information National Post, A4 -side effects not always listed -excuses: people don’t read them anyways.
11. Three provinces halt use of TB-test liquid after patients in Nova Scotia have allergic reactions. National Post -improper testing before releasing to the public. On the same page is an article about Medication mishaps avoidable.
12. Study likely spells end for anti-bleeding drugYahoo News June 14/08 -This one is a doozy. Ok. So Bayer has this drug called Trasylol. They are facing a lawsuit because Trasylol led to excessive deaths and the company hid the evidence of harm. These bad results are supposed to end the production of the drug because numerous studies have shown that the incident of death post-surgery (which is what the drug is for) is increased with this drug. The FDA says that the studies that didn’t show a higher risk were very flawed. Bayer says that they are waiting for results from a Canadian study.
13. FDA stresses birth defect risk with Roche (and Novartis) drugYahoo News June 16/08 -Some of the problems were birth defects, permanent problems with the brain and nervous system, plus, some of the patients were taking the drug CellCept for stuff it wasn’t approved to treat (like lupus or rheumatoid arthritis).
14. Drug-research spending second to marketing:study CTV.ca News Staff. -Big Pharma is spending more on selling drugs than they are spending on research and development. That doesn’t make me feel confident in their product.
About hospitals in Canada:
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Medicine sending thousands to hospital 25% of admissions due to side effects. National Post Nov 1/06 -drug side effects in proper dosages and wrongfully administered drugs (drug names sound and are spelled similar etc.)
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One in 10 receives wrong meds in hospital CTV.ca Aug 14/07 How does that happen in a place full of health professionals?
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To Tell the Truth: The Ethical and Legal Implications of Disclosure of Medical Error by Michael Waite (Stones Fontaine Carbert lawyer in Calgary) -He talks about the implications to hospitals etc. about reporting fault in incidents resulting in death or harm (think administering the wrong drugs) and says that it is very uncommon for a hospital to admit fault to their patient.
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The truth about hospital Ottawa Citizen -”Almost 14,000 people die annually from in-hospital errors.” That is more people dying that people who die from car accidents, HIV and breast cancer combined!
So now that you know this, how can you protect yourself?
Well I own a Pharmaceutical Compendium. Mine is from 1993 and should probably be upgraded but they are very expensive. These books contain a list of ALL the drugs approved for use at that time. It includes information on research, side effects, instructions for use and much more. I never fill a prescription for myself or my family without reading into it more. Remember how I said that I was prescribed a drug (Advair) for my “asthma?” Well it turns out that Advair is a much more dangerous drug for asthma than the alternatives. It states that right in the package insert that came with my free sample. I was outraged. They don’t even know that I have asthma for sure and they are prescribing me a product that is meant to be used as a last line of defense because it is more dangerous than the other drugs. Nice!
I especially like the list of recalled products for the year. It’s very eye opening when something that you or your friend or neighbour was taking is now deemed unsafe for public use.
So to recap, to protect yourself and your family you can become informed. Look into the diseases that you are told you have and make sure that the side effects listed in reference books actually match what you are experiencing. My husband was misdiagnosed once before.
If you agree with the Doctor’s diagnosis then become informed about the drug s/he is prescribing for you. If the possible side-effects make you uncomfortable you can ask to be prescribed something else.
Ask yourself if you need the drugs? Do you have a mild allergy (or a cold or whatever) that could go without drugs? Can you treat it naturally with supplements, vitamins, herbs or perhaps even with your diet?
There are also websites where you can look up drug information as well:
http://www.mayoclinic.com/health/drug-information/DrugHerbIndex
http://www.nlm.nih.gov/medlineplus/druginformation.html
For more information on Pharma lobbying see: Big Bucks, Big Pharma: Marketing Disease and Pushing Drugs http://www.freedocumentaries.org/film.php?id=197
I am going to wrap this up now. I hope you learned something and will use this information to help you make better choices for you and your family. The only person who is invested in your health is you!